T8. NEUROLOGICAL SOFT SIGNS (NSS) IN SCHIZOPHRENIA: AN UPDATE ON THE STATE- VERSUS TRAIT-PERSPECTIVE
نویسندگان
چکیده
منابع مشابه
Neurological Soft Signs in Schizophrenia: An Update on the State- versus Trait-Perspective
Background Neurological soft signs (NSS) represent minor neurological signs, which indicate non-specific cerebral dysfunction. In schizophrenia, their presence has been documented extensively across all stages of the disease. Until recently, NSS were considered an endophenotype or a trait phenomenon. During the past years, however, researchers report fluctuations of the NSS scores. Aims To fu...
متن کاملNeurological Soft Signs in First -Episode Schizophrenia
Neurological soft signs (NSS) refer to subtle neurological abnormalities comprising deficits in sensory integration, motor coordination, or sequencing of complex motor acts. It is generally accepted that NSS are more prevalent in schizophrenia patients, including first -episode cases, than in healthy subjects. Moreover, NSS have been consistently demonstrated in neuroleptic naïve firstepisode p...
متن کاملPotential endophenotype for schizophrenia: neurological soft signs.
INTRODUCTION Neurological soft signs (NSS) are suggested as a candidate endophenotype for schizophrenia. This article aims to review relevant literature and discuss the role of NSS in understanding schizophrenia. METHODS This is an update on a review article published in 2003. Articles from 2003 onwards were specifically reviewed and discussed with relevance to the role of NSS as endophenotyp...
متن کاملThe clinical correlates of neurological soft signs in chronic schizophrenia.
Among 16 chronic schizophrenic in-patients, all had at least one neurological soft sign (NSS), and 6 (40%) had definite neurodysfunction. NSS and TD scores were highly intercorrelated, and NSS were significantly correlated with neuroleptic drug exposure. NSS correlated positively with both positive and negative symptoms and cognitive impairment but not with cerebral ventricular size on CT. Pati...
متن کاملA Comparative Profile of Neurological Soft Signs (NSS) in First Degree Relatives of Schizophrenia, and Bipolar Disorder
Objectives & Aim of the Study: Evidence for the higher prevalence of NSS in schizophrenics and their 1 degree relatives is substantial whereas evidence for the specificity of the subtypes of the NSS is relatively sparse. This study was performed to find out if there is a subset of NSS discriminating 1 degree relatives of schizophrenic when compared with 1 degree relatives of bipolar disorder pa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Schizophrenia Bulletin
سال: 2018
ISSN: 0586-7614,1745-1701
DOI: 10.1093/schbul/sby016.284